The pathological hallmarks of Alzheimer’s disease (AD) include extracellular beta-amyloid plaques, neurofibrillary tangles, neuronal loss and tau deposits in brain. Therapies targeting these known hallmarks are yet to yield any meaningful benefit in clinical trials. We spoke to four researchers in the fields of AD research and therapy development to find out where they think the fields should head next.
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Medical research involves research in a wide range of fields, such as biology, chemistry, pharmacology and toxicology with the goal of developing new medicines or medical procedures or improving the application of those already available. It can be viewed as encompassing preclinical research (for example, in cellular systems and animal models) and clinical research (for example, clinical trials).
The intersection of science, medicine, and computational technology holds unsurpassed promise and importance in the 21st century. At that juncture, the Health Sciences Center for Computational Innovation (HSCCI) facilitates access to high-performance computational resources for biomedical research.
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At URMC, scientists have access to the latest research tools and technologies, a wide range of support services, and experienced faculty and staff to provide guidance and mentorship.
